|5-HTP (5-hydroxytryptophan) is a metabolite of the amino acid tryptophan. You may know tryptophan as the agent in turkey that makes you feel like taking a nap after Thanksgiving dinner (in addition to a full belly). 5-HTP is a direct precursor of the important inhibitory neurotransmitter serotonin, which is secreted in response to mood or emotion swings. Serotonin soothes and calms and brings about feelings of contentment.|
Griffonia simplicifolia is an African plant which is extracted to produce 5-HTP, the intermediate metabolite between the amino acid L-tryptophan and serotonin.
Is 5-HTP safe to take? The FDA has warned that it has found batches with impurities similar to the Japanese batches of tryptophan in 1980.
5-HTP and tryptophan are not the same. 5-HTP is related to tryptophan, but is derived from a different source. The 1980 scare concerning the Japanese tryptophan was attributed to a large batch the Japanese produced that was contaminated during the fermentation and/or filtration process. The contaminant caused affected persons to develop symptoms of EMS (eosinophilia-myalgia syndrome). 5-HTP, unlike tryptophan, is now extracted from the seed of the Griffonia simplicifolia plant and is not produced via bacterial fermentation, virtually eliminating further occurrence of EMS. Although there have been a couple of cases of EMS–like symptoms arising after 5-HTP supplementation, no direct correlations have established, and EMS can occur on its own.
Serving Size: 1 Vcap®
Amount Per Serving % Daily Value
Niacinamide (Vitamin B-3) 10 mg 50%
Vitamin B-6 (from Pyridoxine HCI) 3 mg 150%
L-Tyrosine 250 mg
5-HTP (5-hydroxytryptophan) (from seeds of Griffonia simplicifolia) 200 mg
Suggested Use: As an herbal dietary supplement, take 1 5-HTP Vcap daily, preferably on an empty stomach at bedtime.
Free of: sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg or preservatives.
Warnings: Not for use by pregnant/lactating women or those currently taking any anti-depressant medications unless recommended by a healthcare practitioner. May cause drowsiness. Caution: Please discard the inedible freshness packet enclosed.
Other Ingredients: Cellulose (capsule), Magnesium Stearate (vegetable source) and Silica.